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Trafficking of plasmepsin II to the food vacuole of the malaria parasite Plasmodium falciparum

fA amily of aspartic proteases, the plasmepsins (PMs), plays a key role in the degradation of hemoglobin in the Plasmodium falciparum food vacuole. To study the trafficking of proPM II, we have modified the chromosomal PM II gene in P. falciparum to encode a proPM II–GFP chimera. By taking advantage...

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Detalles Bibliográficos
Autores principales: Klemba, Michael, Beatty, Wandy, Gluzman, Ilya, Goldberg, Daniel E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171955/
https://www.ncbi.nlm.nih.gov/pubmed/14709539
http://dx.doi.org/10.1083/jcb200307147