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i-SNAREs: inhibitory SNAREs that fine-tune the specificity of membrane fusion
A new functional class of SNAREs, designated inhibitory SNAREs (i-SNAREs), is described here. An i-SNARE inhibits fusion by substituting for or binding to a subunit of a fusogenic SNAREpin to form a nonfusogenic complex. Golgi-localized SNAREs were tested for i-SNARE activity by adding them as a fif...
Autores principales: | Varlamov, Oleg, Volchuk, Allen, Rahimian, Vahid, Doege, Claudia A., Paumet, Fabienne, Eng, William S., Arango, Nancy, Parlati, Francesco, Ravazzola, Mariella, Orci, Lelio, Söllner, Thomas H., Rothman, James E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171956/ https://www.ncbi.nlm.nih.gov/pubmed/14699088 http://dx.doi.org/10.1083/jcb.200307066 |
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