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IGF-I instructs multipotent adult neural progenitor cells to become oligodendrocytes

Adult multipotent neural progenitor cells can differentiate into neurons, astrocytes, and oligodendrocytes in the mammalian central nervous system, but the molecular mechanisms that control their differentiation are not yet well understood. Insulin-like growth factor I (IGF-I) can promote the differ...

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Detalles Bibliográficos
Autores principales: Hsieh, Jenny, Aimone, James B., Kaspar, Brian K., Kuwabara, Tomoko, Nakashima, Kinichi, Gage, Fred H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171962/
https://www.ncbi.nlm.nih.gov/pubmed/14709544
http://dx.doi.org/10.1083/jcb.200308101