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Promyelocytic leukemia nuclear bodies associate with transcriptionally active genomic regions

The promyelocytic leukemia (PML) protein is aggregated into nuclear bodies that are associated with diverse nuclear processes. Here, we report that the distance between a locus and its nearest PML body correlates with the transcriptional activity and gene density around the locus. Genes on the activ...

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Detalles Bibliográficos
Autores principales: Wang, Jayson, Shiels, Carol, Sasieni, Peter, Wu, Pei Jun, Islam, Suhail A., Freemont, Paul S., Sheer, Denise
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171989/
https://www.ncbi.nlm.nih.gov/pubmed/14970191
http://dx.doi.org/10.1083/jcb.200305142

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