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Bicarbonate-responsive “soluble” adenylyl cyclase defines a nuclear cAMP microdomain
Bicarbonate-responsive “soluble” adenylyl cyclase resides, in part, inside the mammalian cell nucleus where it stimulates the activity of nuclear protein kinase A to phosphorylate the cAMP response element binding protein (CREB). The existence of this complete and functional, nuclear-localized cAMP...
Autores principales: | Zippin, Jonathan H., Farrell, Jeanne, Huron, David, Kamenetsky, Margarita, Hess, Kenneth C., Fischman, Donald A., Levin, Lonny R., Buck, Jochen |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172001/ https://www.ncbi.nlm.nih.gov/pubmed/14769862 http://dx.doi.org/10.1083/jcb.200311119 |
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