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The mechanism of spindle assembly: functions of Ran and its target TPX2
Recent work has provided new insights into the mechanism of spindle assembly. Growing evidence supports a model in which the small GTPase Ran plays a central role in this process. Here, we examine the evidence for the existence of a RanGTP gradient around mitotic chromosomes and some controversial d...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172015/ https://www.ncbi.nlm.nih.gov/pubmed/15452138 http://dx.doi.org/10.1083/jcb.200312112 |