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Mesenchymal–epithelial interactions in the skin: increased expression of dickkopf1 by palmoplantar fibroblasts inhibits melanocyte growth and differentiation
We investigated whether or not the topographic regulation of melanocyte differentiation is determined by mesenchymal–epithelial interactions via fibroblast-derived factors. The melanocyte density in palmoplantar human skin (i.e., skin on the palms and the soles) is five times lower than that found i...
Autores principales: | Yamaguchi, Yuji, Itami, Satoshi, Watabe, Hidenori, Yasumoto, Ken-ichi, Abdel-Malek, Zalfa A., Kubo, Tateki, Rouzaud, François, Tanemura, Atsushi, Yoshikawa, Kunihiko, Hearing, Vincent J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172049/ https://www.ncbi.nlm.nih.gov/pubmed/15117970 http://dx.doi.org/10.1083/jcb.200311122 |
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