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Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins
The adaptor protein (AP) 3 adaptor complex has been implicated in the transport of lysosomal membrane proteins, but its precise site of action has remained controversial. Here, we show by immuno-electron microscopy that AP-3 is associated with budding profiles evolving from a tubular endosomal compa...
Autores principales: | Peden, Andrew A., Oorschot, Viola, Hesser, Boris A., Austin, Cary D., Scheller, Richard H., Klumperman, Judith |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172074/ https://www.ncbi.nlm.nih.gov/pubmed/15051738 http://dx.doi.org/10.1083/jcb.200311064 |
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