Cargando…

The C2 domain of the Rsp5 ubiquitin ligase binds membrane phosphoinositides and directs ubiquitination of endosomal cargo

Ubiquitin ligases of the Nedd4 family regulate membrane protein trafficking by modifying both cargo proteins and the transport machinery with ubiquitin. Here, we investigate the role of the yeast Nedd4 homologue, Rsp5, in protein sorting into vesicles that bud into the multivesicular endosome (MVE)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dunn, Rebecca, Klos, Deborah A., Adler, Adam S., Hicke, Linda
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172079/ https://www.ncbi.nlm.nih.gov/pubmed/15078904 http://dx.doi.org/10.1083/jcb.200309026

Ejemplares similares

Sodium Acetate Responses in Saccharomyces cerevisiae and the Ubiquitin Ligase Rsp5
por: Watcharawipas, Akaraphol, et al.
Publicado: (2018)

Ubiquitination of ERMES components by the E3 ligase Rsp5 is involved in mitophagy
por: Belgareh-Touzé, Naïma, et al.
Publicado: (2016)

Rsp5 Ubiquitin ligase–mediated quality control system clears membrane proteins mistargeted to the vacuole membrane
por: Sardana, Richa, et al.
Publicado: (2019)

Rsp5 Ubiquitin Ligase Is Required for Protein Trafficking in Saccharomyces cerevisiae COPI Mutants
por: Jarmoszewicz, Katarzyna, et al.
Publicado: (2012)

Profiling and verifying the substrates of E3 ubiquitin ligase Rsp5 in yeast cells
por: Fang, Shuai, et al.
Publicado: (2023)

Identification of the endocytic sorting signal recognized by the Art1-Rsp5 ubiquitin ligase complex
por: Guiney, Evan L., et al.
Publicado: (2016)

A GID E3 ligase assembly ubiquitinates an Rsp5 E3 adaptor and regulates plasma membrane transporters
por: Langlois, Christine R, et al.
Publicado: (2022)

Integrated control of transporter endocytosis and recycling by the arrestin-related protein Rod1 and the ubiquitin ligase Rsp5
por: Becuwe, Michel, et al.
Publicado: (2014)

Rsp5/Nedd4 is the major ubiquitin ligase that targets cytosolic misfolded proteins upon heat-stress
por: Fang, Nancy N., et al.
Publicado: (2014)

Adaptor linked K63 di-ubiquitin activates Nedd4/Rsp5 E3 ligase
por: Zhu, Lu, et al.
Publicado: (2022)

Ubp2 Regulates Rsp5 Ubiquitination Activity In Vivo and In Vitro
por: Lam, Mandy H. Y., et al.
Publicado: (2013)

The ART-Rsp5 ubiquitin ligase network comprises a plasma membrane quality control system that protects yeast cells from proteotoxic stress
por: Zhao, Yingying, et al.
Publicado: (2013)

Identification of the ubiquitin ligase Triad1 as a regulator of endosomal transport
por: Hassink, Gerco, et al.
Publicado: (2012)

ESCRT ubiquitin-binding domains function cooperatively during MVB cargo sorting
por: Shields, S. Brookhart, et al.
Publicado: (2009)

Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast
por: Gupta, Ronish, et al.
Publicado: (2007)

Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes
por: Kazan, Jalal M., et al.
Publicado: (2021)

MARCH ubiquitin ligases alter the itinerary of clathrin-independent cargo from recycling to degradation
por: Eyster, Craig A., et al.
Publicado: (2011)

Regulation of cargo transfer between ESCRT-0 and ESCRT-I complexes by flotillin-1 during endosomal sorting of ubiquitinated cargo
por: Meister, M, et al.
Publicado: (2017)

Ubiquitin ligases and beyond
por: Dikic, Ivan, et al.
Publicado: (2012)

Ubiquitin binding by the CUE domain promotes endosomal localization of the Rab5 GEF Vps9
por: Shideler, Tess, et al.
Publicado: (2015)

AMSH is an endosome-associated ubiquitin isopeptidase
por: McCullough, John, et al.
Publicado: (2004)

UIM domain-dependent recruitment of the endocytic adaptor protein Eps15 to ubiquitin-enriched endosomes
por: Gucwa, Azad L, et al.
Publicado: (2014)

Ubiquitin Ligases in Cholesterol Metabolism
por: Jiang, Wei, et al.
Publicado: (2014)

HERC Ubiquitin Ligases in Cancer
por: Sala-Gaston, Joan, et al.
Publicado: (2020)

Zinc Binding Properties of Engineered RING Finger Domain of Arkadia E3 Ubiquitin Ligase
por: Chasapis, Christos T., et al.
Publicado: (2010)

Regulation of Endocytic Clathrin Dynamics by Cargo Ubiquitination
por: Henry, Anastasia G., et al.
Publicado: (2012)

Cytoplasmic Tail Phosphorylation of the α-Factor Receptor Is Required for Its Ubiquitination and Internalization
por: Hicke, Linda, et al.
Publicado: (1998)

The Role of Membrane-Associated E3 Ubiquitin Ligases in Cancer
por: Chen, Xuankun, et al.
Publicado: (2022)

A single ubiquitin is sufficient for cargo protein entry into MVBs in the absence of ESCRT ubiquitination
por: Stringer, Daniel K., et al.
Publicado: (2011)

A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin
por: Lim, Michael, et al.
Publicado: (2019)

Interaction profiling of RNA-binding ubiquitin ligases reveals a link between posttranscriptional regulation and the ubiquitin system
por: Hildebrandt, Andrea, et al.
Publicado: (2017)

The ubiquitin ligase deltex-3l regulates endosomal sorting of the G protein–coupled receptor CXCR4
por: Holleman, Justine, et al.
Publicado: (2014)

A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes
por: Gschweitl, Michaela, et al.
Publicado: (2016)

Molecular Analysis of Membrane Targeting by the C2 Domain of the E3 Ubiquitin Ligase Smurf1
por: Scott, Jordan L., et al.
Publicado: (2020)

Membrane-anchored ubiquitin ligase complex is required for the turnover of lysosomal membrane proteins
por: Li, Ming, et al.
Publicado: (2015)

Regulation of ubiquitin ligase dynamics by the nucleolus
por: Mekhail, Karim, et al.
Publicado: (2005)

Origin and Diversification of TRIM Ubiquitin Ligases
por: Marín, Ignacio
Publicado: (2012)

Evolution of Plant HECT Ubiquitin Ligases
por: Marín, Ignacio
Publicado: (2013)

RSP5 Positively Regulates the Osteogenic Differentiation of Mesenchymal Stem Cells by Activating the K63-Linked Ubiquitination of Akt
por: Liang, Changxiang, et al.
Publicado: (2020)

Interactions between the quality control ubiquitin ligase CHIP and ubiquitin conjugating enzymes
por: Xu, Zhen, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_68sef9baooa0lgmojngenjbedc