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The ubiquitin proteasome system in synaptic and axonal degeneration: a new twist to an old cycle
The ubiquitin proteasome system (UPS) contributes to the pathophysiology of neurodegenerative diseases, and it is also a major determinant of synaptic protein degradation and activity. Recent studies in rodents and in the fruit fly Drosophila have shown that the activity of the UPS is involved in ax...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2004
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172081/ https://www.ncbi.nlm.nih.gov/pubmed/15067020 http://dx.doi.org/10.1083/jcb.200311091 |