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Mathematical modeling reveals threshold mechanism in CD95-induced apoptosis

Mathematical modeling is required for understanding the complex behavior of large signal transduction networks. Previous attempts to model signal transduction pathways were often limited to small systems or based on qualitative data only. Here, we developed a mathematical modeling framework for unde...

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Detalles Bibliográficos
Autores principales:	Bentele, M., Lavrik, I., Ulrich, M., Stößer, S., Heermann, D.W., Kalthoff, H., Krammer, P.H., Eils, R.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172102/ https://www.ncbi.nlm.nih.gov/pubmed/15364960 http://dx.doi.org/10.1083/jcb.200404158

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