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SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes
TCF and SOX proteins belong to the high mobility group box transcription factor family. Whereas TCFs, the transcriptional effectors of the Wnt pathway, have been widely implicated in the development, homeostasis and disease of the intestine epithelium, little is known about the function of the SOX p...
Autores principales: | Blache, Philippe, van de Wetering, Marc, Duluc, Isabelle, Domon, Claire, Berta, Philippe, Freund, Jean-Noël, Clevers, Hans, Jay, Philippe |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172132/ https://www.ncbi.nlm.nih.gov/pubmed/15240568 http://dx.doi.org/10.1083/jcb.200311021 |
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