DNA damage stabilizes interaction of CSB with the transcription elongation machinery

The Cockayne syndrome B (CSB) protein is essential for transcription-coupled DNA repair (TCR), which is dependent on RNA polymerase II elongation. TCR is required to quickly remove the cytotoxic transcription-blocking DNA lesions. Functional GFP-tagged CSB, expressed at physiological levels, was hom...

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Detalles Bibliográficos
Autores principales: van den Boom, Vincent, Citterio, Elisabetta, Hoogstraten, Deborah, Zotter, Angelika, Egly, Jean-Marc, van Cappellen, Wiggert A., Hoeijmakers, Jan H.J., Houtsmuller, Adriaan B., Vermeulen, Wim
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172148/
https://www.ncbi.nlm.nih.gov/pubmed/15226310
http://dx.doi.org/10.1083/jcb.200401056

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