The peroxisome: orchestrating important developmental decisions from inside the cell

The peroxisome has long been known for its role in lipid metabolism and hydrogen peroxide detoxification. However, growing evidence supports the view that this organelle can also function both as an intracellular signaling compartment and as an organizing platform that orchestrates certain developme...

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Detalles Bibliográficos
Autores principales: Titorenko, Vladimir I., Rachubinski, Richard A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Mini-Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172158/
https://www.ncbi.nlm.nih.gov/pubmed/14981090
http://dx.doi.org/10.1083/jcb.200312081
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author Titorenko, Vladimir I.
Rachubinski, Richard A.
author_facet Titorenko, Vladimir I.
Rachubinski, Richard A.
author_sort Titorenko, Vladimir I.
collection PubMed
description The peroxisome has long been known for its role in lipid metabolism and hydrogen peroxide detoxification. However, growing evidence supports the view that this organelle can also function both as an intracellular signaling compartment and as an organizing platform that orchestrates certain developmental decisions from inside the cell. This review highlights various strategies that peroxisomes employ to regulate the processes of development, differentiation, and morphogenesis and critically evaluates several molecular mechanisms by which peroxisomes promote these processes.
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spelling pubmed-21721582008-03-05 The peroxisome: orchestrating important developmental decisions from inside the cell Titorenko, Vladimir I. Rachubinski, Richard A. J Cell Biol Mini-Review The peroxisome has long been known for its role in lipid metabolism and hydrogen peroxide detoxification. However, growing evidence supports the view that this organelle can also function both as an intracellular signaling compartment and as an organizing platform that orchestrates certain developmental decisions from inside the cell. This review highlights various strategies that peroxisomes employ to regulate the processes of development, differentiation, and morphogenesis and critically evaluates several molecular mechanisms by which peroxisomes promote these processes. The Rockefeller University Press 2004-03-01 /pmc/articles/PMC2172158/ /pubmed/14981090 http://dx.doi.org/10.1083/jcb.200312081 Text en Copyright © 2004, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Mini-Review
Titorenko, Vladimir I.
Rachubinski, Richard A.
The peroxisome: orchestrating important developmental decisions from inside the cell
title The peroxisome: orchestrating important developmental decisions from inside the cell
title_full The peroxisome: orchestrating important developmental decisions from inside the cell
title_fullStr The peroxisome: orchestrating important developmental decisions from inside the cell
title_full_unstemmed The peroxisome: orchestrating important developmental decisions from inside the cell
title_short The peroxisome: orchestrating important developmental decisions from inside the cell
title_sort peroxisome: orchestrating important developmental decisions from inside the cell
topic Mini-Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172158/
https://www.ncbi.nlm.nih.gov/pubmed/14981090
http://dx.doi.org/10.1083/jcb.200312081
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