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Regulation of cell migration and survival by focal adhesion targeting of Lasp-1
Large-scale proteomic and functional analysis of isolated pseudopodia revealed the Lim, actin, and SH3 domain protein (Lasp-1) as a novel protein necessary for cell migration, but not adhesion to, the extracellular matrix (ECM). Lasp-1 is a ubiquitously expressed actin-binding protein with a unique...
Autores principales: | Lin, Yi Hsing, Park, Zee-Yong, Lin, Dayin, Brahmbhatt, Anar A., Rio, Marie-Christine, Yates, John R., Klemke, Richard L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172195/ https://www.ncbi.nlm.nih.gov/pubmed/15138294 http://dx.doi.org/10.1083/jcb.200311045 |
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