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DaPKC-dependent phosphorylation of Crumbs is required for epithelial cell polarity in Drosophila

Both in Drosophila and vertebrate epithelial cells, the establishment of apicobasal polarity requires the apically localized, membrane-associated Par-3–Par-6–aPKC protein complex. In Drosophila, this complex colocalizes with the Crumbs–Stardust (Sdt)–Pals1-associated TJ protein (Patj) complex. Genet...

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Detalles Bibliográficos
Autores principales: Sotillos, Sol, Díaz-Meco, María Teresa, Caminero, Eva, Moscat, Jorge, Campuzano, Sonsoles
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172211/
https://www.ncbi.nlm.nih.gov/pubmed/15302858
http://dx.doi.org/10.1083/jcb.200311031