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Cleavage furrow positioning
To complete the cell cycle, the cleavage furrow draws the plasma membrane toward the cell center, pinching the cytoplasm into two lobes that are subsequently separated into two cells. The position of the cleavage furrow is induced by the mitotic spindle during early anaphase. Although the mechanism...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2004
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172245/ https://www.ncbi.nlm.nih.gov/pubmed/14757750 http://dx.doi.org/10.1083/jcb.200310112 |
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author | Glotzer, Michael |
author_facet | Glotzer, Michael |
author_sort | Glotzer, Michael |
collection | PubMed |
description | To complete the cell cycle, the cleavage furrow draws the plasma membrane toward the cell center, pinching the cytoplasm into two lobes that are subsequently separated into two cells. The position of the cleavage furrow is induced by the mitotic spindle during early anaphase. Although the mechanism of cleavage furrow positioning is not understood at a molecular level, recent results suggest that it might be mediated by local relief from the inhibitory effects of microtubules. |
format | Text |
id | pubmed-2172245 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2004 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21722452008-03-05 Cleavage furrow positioning Glotzer, Michael J Cell Biol Mini-Review To complete the cell cycle, the cleavage furrow draws the plasma membrane toward the cell center, pinching the cytoplasm into two lobes that are subsequently separated into two cells. The position of the cleavage furrow is induced by the mitotic spindle during early anaphase. Although the mechanism of cleavage furrow positioning is not understood at a molecular level, recent results suggest that it might be mediated by local relief from the inhibitory effects of microtubules. The Rockefeller University Press 2004-02-02 /pmc/articles/PMC2172245/ /pubmed/14757750 http://dx.doi.org/10.1083/jcb.200310112 Text en Copyright © 2004, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Mini-Review Glotzer, Michael Cleavage furrow positioning |
title | Cleavage furrow positioning |
title_full | Cleavage furrow positioning |
title_fullStr | Cleavage furrow positioning |
title_full_unstemmed | Cleavage furrow positioning |
title_short | Cleavage furrow positioning |
title_sort | cleavage furrow positioning |
topic | Mini-Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172245/ https://www.ncbi.nlm.nih.gov/pubmed/14757750 http://dx.doi.org/10.1083/jcb.200310112 |
work_keys_str_mv | AT glotzermichael cleavagefurrowpositioning |