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Zinc and the Msc2 zinc transporter protein are required for endoplasmic reticulum function

In this report, we show that zinc is required for endoplasmic reticulum function in Saccharomyces cerevisiae. Zinc deficiency in this yeast induces the unfolded protein response (UPR), a system normally activated by unfolded ER proteins. Msc2, a member of the cation diffusion facilitator (CDF) famil...

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Detalles Bibliográficos
Autores principales:	Ellis, Charissa D., Wang, Fudi, MacDiarmid, Colin W., Clark, Suzanne, Lyons, Thomas, Eide, David J.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172251/ https://www.ncbi.nlm.nih.gov/pubmed/15277543 http://dx.doi.org/10.1083/jcb.200401157

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