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Differential transactivation of sphingosine-1-phosphate receptors modulates NGF-induced neurite extension

The process of neurite extension after activation of the TrkA tyrosine kinase receptor by nerve growth factor (NGF) involves complex signaling pathways. Stimulation of sphingosine kinase 1 (SphK1), the enzyme that phosphorylates sphingosine to form sphingosine-1-phosphate (S1P), is part of the funct...

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Detalles Bibliográficos
Autores principales:	Toman, Rachelle E., Payne, Shawn G., Watterson, Kenneth R., Maceyka, Michael, Lee, Norman H., Milstien, Sheldon, Bigbee, John W., Spiegel, Sarah
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172260/ https://www.ncbi.nlm.nih.gov/pubmed/15289497 http://dx.doi.org/10.1083/jcb.200402016

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