A pathway of neuregulin-induced activation of cofilin-phosphatase Slingshot and cofilin in lamellipodia

Cofilin mediates lamellipodium extension and polarized cell migration by stimulating actin filament dynamics at the leading edge of migrating cells. Cofilin is inactivated by phosphorylation at Ser-3 and reactivated by cofilin-phosphatase Slingshot-1L (SSH1L). Little is known of signaling mechanisms...

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Detalles Bibliográficos
Autores principales: Nagata-Ohashi, Kyoko, Ohta, Yusaku, Goto, Kazumichi, Chiba, Shuhei, Mori, Reiko, Nishita, Michiru, Ohashi, Kazumasa, Kousaka, Kazuyoshi, Iwamatsu, Akihiro, Niwa, Ryusuke, Uemura, Tadashi, Mizuno, Kensaku
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172350/
https://www.ncbi.nlm.nih.gov/pubmed/15159416
http://dx.doi.org/10.1083/jcb.200401136

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