Cargando…

53BP1 is required for class switch recombination

53BP1 participates early in the DNA damage response and is involved in cell cycle checkpoint control. Moreover, the phenotype of mice and cells deficient in 53BP1 suggests a defect in DNA repair (Ward et al., 2003b). Therefore, we asked whether or not 53BP1 would be required for the efficient repair...

Descripción completa

Detalles Bibliográficos
Autores principales: Ward, Irene M., Reina-San-Martin, Bernardo, Olaru, Alexandru, Minn, Kay, Tamada, Koji, Lau, Julie S., Cascalho, Marilia, Chen, Lieping, Nussenzweig, Andre, Livak, Ferenc, Nussenzweig, Michel C., Chen, Junjie
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172356/
https://www.ncbi.nlm.nih.gov/pubmed/15159415
http://dx.doi.org/10.1083/jcb.200403021