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53BP1 is required for class switch recombination
53BP1 participates early in the DNA damage response and is involved in cell cycle checkpoint control. Moreover, the phenotype of mice and cells deficient in 53BP1 suggests a defect in DNA repair (Ward et al., 2003b). Therefore, we asked whether or not 53BP1 would be required for the efficient repair...
Autores principales: | Ward, Irene M., Reina-San-Martin, Bernardo, Olaru, Alexandru, Minn, Kay, Tamada, Koji, Lau, Julie S., Cascalho, Marilia, Chen, Lieping, Nussenzweig, Andre, Livak, Ferenc, Nussenzweig, Michel C., Chen, Junjie |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172356/ https://www.ncbi.nlm.nih.gov/pubmed/15159415 http://dx.doi.org/10.1083/jcb.200403021 |
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