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Integrin α(V)β(6)-mediated activation of latent TGF-β requires the latent TGF-β binding protein-1

Transforming growth factor-βs (TGF-β) are secreted as inactive complexes containing the TGF-β, the TGF-β propeptide, also called the latency-associated protein (LAP), and the latent TGF-β binding protein (LTBP). Extracellular activation of this complex is a critical but incompletely understood step...

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Detalles Bibliográficos
Autores principales:	Annes, Justin P., Chen, Yan, Munger, John S., Rifkin, Daniel B.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172370/ https://www.ncbi.nlm.nih.gov/pubmed/15184403 http://dx.doi.org/10.1083/jcb.200312172

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