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Trafficking of Lyn through the Golgi caveolin involves the charged residues on αE and αI helices in the kinase domain
Src-family kinases, known to participate in signaling pathways of a variety of surface receptors, are localized to the cytoplasmic side of the plasma membrane through lipid modification. We show here that Lyn, a member of the Src-family kinases, is biosynthetically transported to the plasma membrane...
Autores principales: | Kasahara, Kousuke, Nakayama, Yuji, Ikeda, Kikuko, Fukushima, Yuka, Matsuda, Daisuke, Horimoto, Shinya, Yamaguchi, Naoto |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172378/ https://www.ncbi.nlm.nih.gov/pubmed/15173188 http://dx.doi.org/10.1083/jcb.200403011 |
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