Nucleocytoplasmic shuttling by nucleoporins Nup153 and Nup214 and CRM1-dependent nuclear export control the subcellular distribution of latent Stat1

Interferon stimulation of cells leads to the tyrosine phosphorylation of latent Stat1 and subsequent transient accumulation in the nucleus that requires canonical transport factors. However, the mechanisms that control the predominantly cytoplasmic localization in unstimulated cells have not been re...

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Detalles Bibliográficos
Autores principales: Marg, Andreas, Shan, Ying, Meyer, Thomas, Meissner, Torsten, Brandenburg, Martin, Vinkemeier, Uwe
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172394/
https://www.ncbi.nlm.nih.gov/pubmed/15210729
http://dx.doi.org/10.1083/jcb.200403057

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