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Bro1 coordinates deubiquitination in the multivesicular body pathway by recruiting Doa4 to endosomes
Ubiquitination directs the sorting of cell surface receptors and other integral membrane proteins into the multivesicular body (MVB) pathway. Cargo proteins are subsequently deubiquitinated before their enclosure within MVB vesicles. In Saccharomyces cerevisiae, Bro1 functions at a late step of MVB...
Autores principales: | Luhtala, Natalie, Odorizzi, Greg |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172414/ https://www.ncbi.nlm.nih.gov/pubmed/15326198 http://dx.doi.org/10.1083/jcb.200403139 |
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