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DNA replication checkpoint control of Wee1 stability by vertebrate Hsl7

G2/M checkpoints prevent mitotic entry upon DNA damage or replication inhibition by targeting the Cdc2 regulators Cdc25 and Wee1. Although Wee1 protein stability is regulated by DNA-responsive checkpoints, the vertebrate pathways controlling Wee1 degradation have not been elucidated. In budding yeas...

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Detalles Bibliográficos
Autores principales:	Yamada, Ayumi, Duffy, Brad, Perry, Jennifer A., Kornbluth, Sally
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172454/ https://www.ncbi.nlm.nih.gov/pubmed/15583029 http://dx.doi.org/10.1083/jcb.200406048

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