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Contrasting nuclear dynamics of the caspase-activated DNase (CAD) in dividing and apoptotic cells

Although compelling evidence supports the central role of caspase-activated DNase (CAD) in oligonucleosomal DNA fragmentation in apoptotic nuclei, the regulation of CAD activity remains elusive in vivo. We used fluorescence photobleaching and biochemical techniques to investigate the molecular dynam...

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Detalles Bibliográficos
Autores principales:	Lechardeur, Delphine, Xu, Ming, Lukacs, Gergely L.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172457/ https://www.ncbi.nlm.nih.gov/pubmed/15569712 http://dx.doi.org/10.1083/jcb.200404105

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