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Human Rif1 protein binds aberrant telomeres and aligns along anaphase midzone microtubules

We identified and characterized a human orthologue of Rif1 protein, which in budding yeast interacts in vivo with the major duplex telomeric DNA binding protein Rap1p and negatively regulates telomere length. Depletion of hRif1 by RNA interference in human cancer cells impaired cell growth but had n...

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Detalles Bibliográficos
Autores principales:	Xu, Lifeng, Blackburn, Elizabeth H.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172464/ https://www.ncbi.nlm.nih.gov/pubmed/15583028 http://dx.doi.org/10.1083/jcb.200408181

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