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HIV-1 Nef disrupts MHC-I trafficking by recruiting AP-1 to the MHC-I cytoplasmic tail
To avoid immune recognition by cytotoxic T lymphocytes (CTLs), human immunodeficiency virus (HIV)-1 Nef disrupts the transport of major histocompatibility complex class I molecules (MHC-I) to the cell surface in HIV-infected T cells. However, the mechanism by which Nef does this is unknown. We repor...
Autores principales: | Roeth, Jeremiah F., Williams, Maya, Kasper, Matthew R., Filzen, Tracey M., Collins, Kathleen L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172469/ https://www.ncbi.nlm.nih.gov/pubmed/15569716 http://dx.doi.org/10.1083/jcb.200407031 |
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