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Balancing Akt with S6K: implications for both metabolic diseases and tumorigenesis
Proper regulation of the phosphoinositide 3-kinase–Akt pathway is critical for the prevention of both insulin resistance and tumorigenesis. Many recent studies have characterized a negative feedback loop in which components of one downstream branch of this pathway, composed of the mammalian target o...
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| Formato: | Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172491/ https://www.ncbi.nlm.nih.gov/pubmed/15533996 http://dx.doi.org/10.1083/jcb.200408161 |