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Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation
Plakophilins are proteins of the armadillo family that function in embryonic development and in the adult, and when mutated can cause disease. We have ablated the plakophilin 2 gene in mice. The resulting mutant mice exhibit lethal alterations in heart morphogenesis and stability at mid-gestation (E...
Autores principales: | Grossmann, Katja S., Grund, Christine, Huelsken, Joerg, Behrend, Martin, Erdmann, Bettina, Franke, Werner W., Birchmeier, Walter |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172504/ https://www.ncbi.nlm.nih.gov/pubmed/15479741 http://dx.doi.org/10.1083/jcb.200402096 |
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