Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response

Stress-induced eukaryotic translation initiation factor 2 (eIF2) α phosphorylation paradoxically increases translation of the metazoan activating transcription factor 4 (ATF4), activating the integrated stress response (ISR), a pro-survival gene expression program. Previous studies implicated the 5′...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Phoebe D., Harding, Heather P., Ron, David
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172506/
https://www.ncbi.nlm.nih.gov/pubmed/15479734
http://dx.doi.org/10.1083/jcb.200408003

Ejemplares similares

Ejemplares similares