Cargando…

COPII-dependent export of cystic fibrosis transmembrane conductance regulator from the ER uses a di-acidic exit code

Cystic fibrosis (CF) is a childhood hereditary disease in which the most common mutant form of the CF transmembrane conductance regulator (CFTR) ΔF508 fails to exit the endoplasmic reticulum (ER). Export of wild-type CFTR from the ER requires the coat complex II (COPII) machinery, as it is sensitive...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xiaodong, Matteson, Jeanne, An, Yu, Moyer, Bryan, Yoo, Jin-San, Bannykh, Sergei, Wilson, Ian A., Riordan, John R., Balch, William E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172508/
https://www.ncbi.nlm.nih.gov/pubmed/15479737
http://dx.doi.org/10.1083/jcb.200401035

Ejemplares similares