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Roles of p-ERM and Rho–ROCK signaling in lymphocyte polarity and uropod formation

Front–rear asymmetry in motile cells is crucial for efficient directional movement. The uropod in migrating lymphocytes is a posterior protrusion in which several proteins, including CD44 and ezrin/radixin/moesin (ERM), are concentrated. In EL4.G8 T-lymphoma cells, Thr567 phosphorylation in the COOH...

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Detalles Bibliográficos
Autores principales:	Lee, Jong-Hwan, Katakai, Tomoya, Hara, Takahiro, Gonda, Hiroyuki, Sugai, Manabu, Shimizu, Akira
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172551/ https://www.ncbi.nlm.nih.gov/pubmed/15504914 http://dx.doi.org/10.1083/jcb.200403091

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