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MT1-MMP–dependent neovessel formation within the confines of the three-dimensional extracellular matrix

During angiogenesis, endothelial cells initiate a tissue-invasive program within an interstitial matrix comprised largely of type I collagen. Extracellular matrix–degradative enzymes, including the matrix metalloproteinases (MMPs) MMP-2 and MMP-9, are thought to play key roles in angiogenesis by bin...

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Detalles Bibliográficos
Autores principales: Chun, Tae-Hwa, Sabeh, Farideh, Ota, Ichiro, Murphy, Hedwig, McDonagh, Kevin T., Holmbeck, Kenn, Birkedal-Hansen, Henning, Allen, Edward D., Weiss, Stephen J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172577/
https://www.ncbi.nlm.nih.gov/pubmed/15545316
http://dx.doi.org/10.1083/jcb.200405001