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Roles of uroplakins in plaque formation, umbrella cell enlargement, and urinary tract diseases

The apical surface of mouse urothelium is covered by two-dimensional crystals (plaques) of uroplakin (UP) particles. To study uroplakin function, we ablated the mouse UPII gene. A comparison of the phenotypes of UPII- and UPIII-deficient mice yielded new insights into the mechanism of plaque formati...

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Detalles Bibliográficos
Autores principales: Kong, Xiang-Tian, Deng, Fang-Ming, Hu, Ping, Liang, Feng-Xia, Zhou, Ge, Auerbach, Anna B., Genieser, Nancy, Nelson, Peter K., Robbins, Edith S., Shapiro, Ellen, Kachar, Bechara, Sun, Tung-Tien
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172608/
https://www.ncbi.nlm.nih.gov/pubmed/15611339
http://dx.doi.org/10.1083/jcb.200406025