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Roles of uroplakins in plaque formation, umbrella cell enlargement, and urinary tract diseases
The apical surface of mouse urothelium is covered by two-dimensional crystals (plaques) of uroplakin (UP) particles. To study uroplakin function, we ablated the mouse UPII gene. A comparison of the phenotypes of UPII- and UPIII-deficient mice yielded new insights into the mechanism of plaque formati...
Autores principales: | Kong, Xiang-Tian, Deng, Fang-Ming, Hu, Ping, Liang, Feng-Xia, Zhou, Ge, Auerbach, Anna B., Genieser, Nancy, Nelson, Peter K., Robbins, Edith S., Shapiro, Ellen, Kachar, Bechara, Sun, Tung-Tien |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172608/ https://www.ncbi.nlm.nih.gov/pubmed/15611339 http://dx.doi.org/10.1083/jcb.200406025 |
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