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Developmentally regulated alterations in Polycomb repressive complex 1 proteins on the inactive X chromosome

Polycomb group (PcG) proteins belonging to the polycomb (Pc) repressive complexes 1 and 2 (PRC1 and PRC2) maintain homeotic gene silencing. In Drosophila, PRC2 methylates histone H3 on lysine 27, and this epigenetic mark facilitates recruitment of PRC1. Mouse PRC2 (mPRC2) has been implicated in X in...

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Detalles Bibliográficos
Autores principales:	Plath, Kathrin, Talbot, Dale, Hamer, Karien M., Otte, Arie P., Yang, Thomas P., Jaenisch, Rudolf, Panning, Barbara
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172612/ https://www.ncbi.nlm.nih.gov/pubmed/15596546 http://dx.doi.org/10.1083/jcb.200409026

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