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The interplay of osteogenesis and hematopoiesis: expression of a constitutively active PTH/PTHrP receptor in osteogenic cells perturbs the establishment of hematopoiesis in bone and of skeletal stem cells in the bone marrow
The ontogeny of bone marrow and its stromal compartment, which is generated from skeletal stem/progenitor cells, was investigated in vivo and ex vivo in mice expressing constitutively active parathyroid hormone/parathyroid hormone–related peptide receptor (PTH/PTHrP; caPPR) under the control of the...
Autores principales: | Kuznetsov, Sergei A., Riminucci, Mara, Ziran, Navid, Tsutsui, Takeo W., Corsi, Alessandro, Calvi, Laura, Kronenberg, Henry M., Schipani, Ernestina, Robey, Pamela Gehron, Bianco, Paolo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172616/ https://www.ncbi.nlm.nih.gov/pubmed/15611335 http://dx.doi.org/10.1083/jcb.200408079 |
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