Cargando…
Muscle ring finger protein-1 inhibits PKCε activation and prevents cardiomyocyte hypertrophy
Much effort has focused on characterizing the signal transduction cascades that are associated with cardiac hypertrophy. In spite of this, we still know little about the mechanisms that inhibit hypertrophic growth. We define a novel anti-hypertrophic signaling pathway regulated by muscle ring finger...
Autores principales: | Arya, Ranjana, Kedar, Vishram, Hwang, Jae Ryoung, McDonough, Holly, Li, Hui-Hua, Taylor, Joan, Patterson, Cam |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172633/ https://www.ncbi.nlm.nih.gov/pubmed/15596539 http://dx.doi.org/10.1083/jcb.200402033 |
Ejemplares similares
-
Reduced Apaf-1 levels in cardiomyocytes engage strict regulation of apoptosis by endogenous XIAP
por: Potts, Malia B., et al.
Publicado: (2005) -
Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins
por: Li, Hui-Hua, et al.
Publicado: (2022) -
Differential Roles of the PKC Novel Isoforms, PKCδ and PKCε, in Mouse and Human Platelets
por: Pears, Catherine J., et al.
Publicado: (2008) -
Kinetics of PKCε Activating and Inhibiting Llama Single Chain Antibodies and Their Effect on PKCε Translocation in HeLa Cells
por: Summanen, Milla, et al.
Publicado: (2012) -
Identification of hypertrophy-modulating Cullin-RING ubiquitin ligases in primary cardiomyocytes
por: Fischer, Maximillian, et al.
Publicado: (2023)