Traffic-independent function of the Sar1p/COPII machinery in proteasomal sorting of the cystic fibrosis transmembrane conductance regulator

Newly synthesized proteins that do not fold correctly in the ER are targeted for ER-associated protein degradation (ERAD) through distinct sorting mechanisms; soluble ERAD substrates require ER-Golgi transport and retrieval for degradation, whereas transmembrane ERAD substrates are retained in the E...

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Detalles Bibliográficos
Autores principales: Fu, Lianwu, Sztul, Elizabeth
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172646/
https://www.ncbi.nlm.nih.gov/pubmed/12538638
http://dx.doi.org/10.1083/jcb.200210086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172646/
https://www.ncbi.nlm.nih.gov/pubmed/12538638
http://dx.doi.org/10.1083/jcb.200210086

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