Cargando…

EPLIN regulates actin dynamics by cross-linking and stabilizing filaments

Epithelial protein lost in neoplasm (EPLIN) is a cytoskeleton-associated protein encoded by a gene that is down-regulated in transformed cells. EPLIN increases the number and size of actin stress fibers and inhibits membrane ruffling induced by Rac. EPLIN has at least two actin binding sites. Purifi...

Descripción completa

Detalles Bibliográficos
Autores principales: Maul, Raymond S., Song, Yuhong, Amann, Kurt J., Gerbin, Sachi C., Pollard, Thomas D., Chang, David D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172667/
https://www.ncbi.nlm.nih.gov/pubmed/12566430
http://dx.doi.org/10.1083/jcb.200212057