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EPLIN regulates actin dynamics by cross-linking and stabilizing filaments
Epithelial protein lost in neoplasm (EPLIN) is a cytoskeleton-associated protein encoded by a gene that is down-regulated in transformed cells. EPLIN increases the number and size of actin stress fibers and inhibits membrane ruffling induced by Rac. EPLIN has at least two actin binding sites. Purifi...
Autores principales: | Maul, Raymond S., Song, Yuhong, Amann, Kurt J., Gerbin, Sachi C., Pollard, Thomas D., Chang, David D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172667/ https://www.ncbi.nlm.nih.gov/pubmed/12566430 http://dx.doi.org/10.1083/jcb.200212057 |
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