Anthrax toxin triggers endocytosis of its receptor via a lipid raft–mediated clathrin-dependent process

The protective antigen (PA) of the anthrax toxin binds to a cell surface receptor and thereby allows lethal factor (LF) to be taken up and exert its toxic effect in the cytoplasm. Here, we report that clustering of the anthrax toxin receptor (ATR) with heptameric PA or with an antibody sandwich caus...

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Detalles Bibliográficos
Autores principales: Abrami, Laurence, Liu, Shihui, Cosson, Pierre, Leppla, Stephen H., van der Goot, F. Gisou
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172673/
https://www.ncbi.nlm.nih.gov/pubmed/12551953
http://dx.doi.org/10.1083/jcb.200211018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172673/
https://www.ncbi.nlm.nih.gov/pubmed/12551953
http://dx.doi.org/10.1083/jcb.200211018

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