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Anthrax toxin triggers endocytosis of its receptor via a lipid raft–mediated clathrin-dependent process
The protective antigen (PA) of the anthrax toxin binds to a cell surface receptor and thereby allows lethal factor (LF) to be taken up and exert its toxic effect in the cytoplasm. Here, we report that clustering of the anthrax toxin receptor (ATR) with heptameric PA or with an antibody sandwich caus...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172673/ https://www.ncbi.nlm.nih.gov/pubmed/12551953 http://dx.doi.org/10.1083/jcb.200211018 |