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Dynactin polices two-way organelle traffic
How is the bidirectional motion of organelles controlled? In this issue, Deacon et al. (2003) reveal the unexpected finding that dynactin (previously known to control dynein-based motility) binds to kinesin II and regulates anterograde movement of Xenopus melanosomes. This result suggests that dynac...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2003
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172678/ https://www.ncbi.nlm.nih.gov/pubmed/12566424 http://dx.doi.org/10.1083/jcb.200301040 |
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author | Dell, Karen R. |
author_facet | Dell, Karen R. |
author_sort | Dell, Karen R. |
collection | PubMed |
description | How is the bidirectional motion of organelles controlled? In this issue, Deacon et al. (2003) reveal the unexpected finding that dynactin (previously known to control dynein-based motility) binds to kinesin II and regulates anterograde movement of Xenopus melanosomes. This result suggests that dynactin may be a key player in coordinating vesicle traffic in this system. |
format | Text |
id | pubmed-2172678 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2003 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21726782008-05-01 Dynactin polices two-way organelle traffic Dell, Karen R. J Cell Biol Comment How is the bidirectional motion of organelles controlled? In this issue, Deacon et al. (2003) reveal the unexpected finding that dynactin (previously known to control dynein-based motility) binds to kinesin II and regulates anterograde movement of Xenopus melanosomes. This result suggests that dynactin may be a key player in coordinating vesicle traffic in this system. The Rockefeller University Press 2003-02-03 /pmc/articles/PMC2172678/ /pubmed/12566424 http://dx.doi.org/10.1083/jcb.200301040 Text en Copyright © 2003, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Comment Dell, Karen R. Dynactin polices two-way organelle traffic |
title | Dynactin polices two-way organelle traffic |
title_full | Dynactin polices two-way organelle traffic |
title_fullStr | Dynactin polices two-way organelle traffic |
title_full_unstemmed | Dynactin polices two-way organelle traffic |
title_short | Dynactin polices two-way organelle traffic |
title_sort | dynactin polices two-way organelle traffic |
topic | Comment |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172678/ https://www.ncbi.nlm.nih.gov/pubmed/12566424 http://dx.doi.org/10.1083/jcb.200301040 |
work_keys_str_mv | AT dellkarenr dynactinpolicestwowayorganelletraffic |