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Importin β contains a COOH-terminal nucleoporin binding region important for nuclear transport
Proteins containing a classical NLS are transported into the nucleus by the import receptor importin β, which binds to cargoes via the adaptor importin α. The import complex is translocated through the nuclear pore complex by interactions of importin β with a series of nucleoporins. Previous studies...
Autores principales: | Bednenko, Janna, Cingolani, Gino, Gerace, Larry |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172684/ https://www.ncbi.nlm.nih.gov/pubmed/12885761 http://dx.doi.org/10.1083/jcb.200303085 |
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