Cargando…
Direct cadherin-activated cell signaling: a view from the plasma membrane
Classical cadherin adhesion molecules are key determinants of cell recognition and tissue morphogenesis, with diverse effects on cell behavior. Recent developments indicate that classical cadherins are adhesion-activated signaling receptors. In particular, early–immediate Rac signaling is emerging a...
Autores principales: | , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172751/ https://www.ncbi.nlm.nih.gov/pubmed/12507993 http://dx.doi.org/10.1083/jcb.200208156 |
_version_ | 1782145103556509696 |
---|---|
author | Yap, Alpha S. Kovacs, Eva M. |
author_facet | Yap, Alpha S. Kovacs, Eva M. |
author_sort | Yap, Alpha S. |
collection | PubMed |
description | Classical cadherin adhesion molecules are key determinants of cell recognition and tissue morphogenesis, with diverse effects on cell behavior. Recent developments indicate that classical cadherins are adhesion-activated signaling receptors. In particular, early–immediate Rac signaling is emerging as a mechanism to coordinate cadherin–actin integration at the plasma membrane. |
format | Text |
id | pubmed-2172751 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2003 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21727512008-05-01 Direct cadherin-activated cell signaling: a view from the plasma membrane Yap, Alpha S. Kovacs, Eva M. J Cell Biol Mini-Review Classical cadherin adhesion molecules are key determinants of cell recognition and tissue morphogenesis, with diverse effects on cell behavior. Recent developments indicate that classical cadherins are adhesion-activated signaling receptors. In particular, early–immediate Rac signaling is emerging as a mechanism to coordinate cadherin–actin integration at the plasma membrane. The Rockefeller University Press 2003-01-06 /pmc/articles/PMC2172751/ /pubmed/12507993 http://dx.doi.org/10.1083/jcb.200208156 Text en Copyright © 2003, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Mini-Review Yap, Alpha S. Kovacs, Eva M. Direct cadherin-activated cell signaling: a view from the plasma membrane |
title | Direct cadherin-activated cell signaling: a view from the plasma membrane |
title_full | Direct cadherin-activated cell signaling: a view from the plasma membrane |
title_fullStr | Direct cadherin-activated cell signaling: a view from the plasma membrane |
title_full_unstemmed | Direct cadherin-activated cell signaling: a view from the plasma membrane |
title_short | Direct cadherin-activated cell signaling: a view from the plasma membrane |
title_sort | direct cadherin-activated cell signaling: a view from the plasma membrane |
topic | Mini-Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172751/ https://www.ncbi.nlm.nih.gov/pubmed/12507993 http://dx.doi.org/10.1083/jcb.200208156 |
work_keys_str_mv | AT yapalphas directcadherinactivatedcellsignalingaviewfromtheplasmamembrane AT kovacsevam directcadherinactivatedcellsignalingaviewfromtheplasmamembrane |