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Alternating metabolic pathways in NGF-deprived sympathetic neurons affect caspase-independent death

Mitochondrial release of cytochrome c in apoptotic cells activates caspases, which execute apoptotic cell death. However, the events themselves that culminate in caspase activation can have deleterious effects because caspase inhibitor–saved cells ultimately die in a caspase-independent manner. To d...

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Detalles Bibliográficos
Autores principales: Chang, Louis K., Schmidt, Robert E., Johnson, Eugene M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172806/
https://www.ncbi.nlm.nih.gov/pubmed/12876275
http://dx.doi.org/10.1083/jcb.200302109